Artikler
Artikler af Jette Goller Kloth
Indledende ord
Artikler indenfor det psykologfaglige samt forskningsartikler udfærdiget i forlængelse af udført forskning indenfor en ”new mode of action” i forståelsen af udviklingen af alvorlig sygdom, samt behandling af disse med hovedvægten på hjernesygdomme.
Artikler
- Skabelse af positiv energi der beskytter mod sygdom:
- Forskningsartikler:
- Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism, Anne Skøttrup Mørkholt, Ove Wiborg, Jette Goller Kloth Nieland, Søren Nielsen, John Dirk Nieland. Scientific Reports, 2019. Anne Skøttrup Mørkholt has revived Ph.d in jan 2019.
- Research Article 25.05.2017: Experimental autoimmune encephalomyelitis (EAE) models of MS were established to test the efficacy of the CPT1 blocker, Etomoxir. Western Blotting was executed in order to test antibody response against brain proteins in EAE animal sera. Antigens recognized by autoantibodies were immunoprecipitated and analyzed by mass spectrometry with the purpose to identify these antigens, and thereby identifying a correlation between MS and brain antigens.
- Inhibition of carnitine palmitoyl transferase 1 potently treats experimental allergic encephalitis, Anne Skøttrup Mørkholt, Agnete Larsen Shohreh Issazadeh-Navikas, Laura Arbour, Michal Krystian Okliski, Jette Goller kloth Nieland, Tae-Hwan Kwon, Søren Nielsen, John Dirk Nieland. 2019
- Research Article 16.11.2019: Multiple sclerosis (MS) is an inflammatory autoimmune disease in the central nervous system (CNS) characterized by demyelination, inflammatory plaques, oxidative stress and degradation of the blood-brain barrier (BBB)1,2. The etiology of MS is still not fully understood; however, different hypotheses involving infiltration of peripheral T cells activated by molecular mimicry or bystander activation, which triggers the immune system, have been proposed3.
- Research Article 26.05.2020: Pharmacological inhibition of carnitine palmitoyl transferase 1 inhibits and reverses experimental autoimmune encephalitis in rodents Mørkholt, Anne Skøttrup; Oklinski, Michal Krystian; Larsen, Agnete; Bockermann, Robert; Issazadeh-Navikas, Shohreh; Nieland, Jette Goller Kloth; Kwon, Tae-Hwan; Corthals, Angelique; Nielsen, Søren; Nieland, John Dirk Vestergaard
- Research Article 24.09.2020: Dysregulation of metabolic pathways by carnitine palmitoyl-transferase 1 plays a key role in central nervous system disorders: experimental evidence based on animal models